Young Investigator Grant for Probiotics Research
supported by the Global Probiotcs CouncilDANONEYakult
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* Basic research can involve bacteria, cell lines, derived cells or animal models, but does not involve clinical studies in human subjects. However, it can include research on human specimens.

Grant Program

Statement of Purpose

The purpose of the Young Investigator Grant for Probiotics Research (YIGPRO) is to contribute to the advancement of probiotics and gastrointestinal microbiota research in the United States.

Who Should Apply

This program seeks to support the best science that addresses the grant objectives. Attempts will be made to support young investigators who do not yet have independent funding (such as NIH R series awards that are likely to progress to RO1 research awards), Young investigators who are senior fellows with a committed faculty appointment or early faculty members within a maximum of 5 consecutive years of his/her first faculty appointment (appointments must be in the United States) are eligible. Applicants must be interested in understanding the health benefits of probiotics or microbiota and the relationship between probiotics, gastrointestinal microbiota and the body. Candidates must be part of an established research program with the capacity to do research on microbiota and its role in health and disease. Applicants are limited to one submission per investigator.

Grant Program Objectives

  • To stimulate innovative research relevant to the field of gastrointestinal microbiota in the United States
  • To impact academic and career development of young investigators in the United States and attract them into the field of probiotics and gastrointestinal microbiota
  • To provide preliminary data for future funding from NIH and other funding sources

Grant Research Focus for 2014

The focus of the 2014 grant is to improve understanding of mechanisms by which potential probiotics, including beneficial commensals, interact with the host and gastrointestinal microbiota to improve physiology and bodily function.

Proposals on dietary intervention to improve physiological function, health status and reduce disease risk are preferred over proposals on disease pathogenesis, drugs and therapies.

Research cannot employ commercial probiotic strains, but publicly available, non-commercial strains are acceptable.

Grant Information and Maximum Funding Amount

The annual grant amount is $50,000 per grant recipient with a maximum of 10% of this amount dedicated to overhead costs. Three grants will be funded per year with each given to different institutions in the United States. Funds may be used for technical support and supplies. Principal investigator salaries and travel are not funded. Equipment is rarely funded and only when it is critical to the project, is not available through the institution’s core facilities, and receives approval in advance from The Global Probiotics Council.  Under exceptional circumstances a second year will be considered on a competitive basis.

Funding will run from July 2014 to June 2015.

The US Probiotics Scientific Board Grant Selection Committee

The Grant Selection Committee of the US Probiotic Scientific Board is comprised of expert scientists in the fields of gastroenterology, immunology, microbiology, infectious disease, pediatrics, nutrition, and probiotics.  These individuals will provide a scientific review of all applications. The grants will be awarded at the sole discretion of the Selection Committee.

The Grant Selection Committee members include:

Richard Guerrant, MD
Director, Center for Global Health
University of Virginia School of Medicine
Thomas H. Hunter Professor of International Medicine
Division of Infectious Diseases and International Health

James B. Kaper, PhD
Chair, Department of Microbiology and Immunology
University of Maryland School of Medicine

Todd Klaenhammer, PhD
Distinguished University Professor and William Neal Reynolds Professor
Department of Food, Bioprocessing and Nutrition Sciences
North Carolina State University

Balfour Sartor, MD
Director, Multidisciplinary Center for Inflammatory Bowel Disease Research and Treatment
University of North Carolina at Chapel Hill

W. Allan Walker, MD
Conrad Taff Professor of Nutrition, Professor of Pediatrics,
Harvard Medical School
Director, Mucosal Immunology Laboratory,
Massachusetts General Hospital

Previous Awardees

2013
Next-generation Probiotic Discovery for Intestinal Inflammatory and Motility Disorders Using “Humanized” Gnotobiotic Mice
Neelendu Dey, M.D.
Instructor in Medicine and Gastroenterology
Center for Genome Sciences & Systems Biology
Washington University in St. Louis School of Medicine

Bacterial Metabolites Mediate Effect of Gut Microbiota on Gastrointestinal Motility
Purna Kashyap, M.D.
Assistant Professor of Medicine
Mayo Clinic, Gastroenterology and Hepatology

Elucidating the Role of the Intestinal Microbiome in Protein-Energy Undernutrition
Geoffrey Preidis, M.D., Ph.D.
Assistant Professor of Pediatrics
Pediatric Resident
Baylor College of Medicine

2012
Connecting Interpersonal Microbial Variation to Drug Efficacy
Andrew Goodman, PhD
Assistant Professor
Department of Microbial Pathogenesis
Yale University

Augmenting Mucosal Immunity to Prevent Candida albicans Infections
Andrew Koh, M.D.
Assistant Professor
Department of Pediatrics and Microbiology
University of Texas Southwestern Medical Center

2011
Host Responses to Mucus Layer Colonization by Commensal Microbiota Species
Eric Martens, PhD
Assistant Professor
Department of Microbiology and Immunology
University of Michigan Medical School

Interactions of the Yeast, Candida albicans, with the Bacterial Gut Microbiota in Health and Disease
Suzanne Noble, MD, PhD
Assistant Professor
Department of Medicine
Department of Microbiology and Immunology
University of California, San Francisco School of Medicine

2010
The Role of Intestinal Microbiota in Increased Levels of Fecal Serine Proteases and Intestinal Permeability Using Diarrhea-Predominant Irritable Bowel Syndrome as a Model
Ian Carroll, PhD
Research Assistant Professor
Division of Gastroenterology & Hepatology
University of North Carolina at Chapel Hill

A Gene-to-Molecule Approach to Discovering New Antibiotics from Probiotic Bacteria
Michael Fischbach, PhD
Assistant Professor
Department of Bioengineering and Therapeutic Sciences
University of California, San Francisco

2009
Protective Role of Baker’s Yeast in Colonic Inflammation and Cancer
Xinhua Chen, PhD
Instructor in Medicine
Division of Gastroenterology
Beth Israel Deaconess Medical Center
Harvard Medical School

The Influence of Novel Oligopeptides Produced by Transgenic Bacteria on Intestinal Injury due to C. difficile Infection
Glynis Kolling, PhD
Research Associate
Department of Medicine and Infectious Diseases
University of Virginia

2008
Probiotics Protects from Radiation Induced Intestinal Injury: Mechanisms of Action
Mathew Ciorba, MD
Instructor
Division of Gastroenterology
Washington University in St. Louis School of Medicine

Antimicrobial Peptide Mediated Alterations of the Gut Microbiome in Nod2/IL-10 Deficient Mice
Ajay Gulati, MD
Research Assistant Professor
Department of Pediatric Gastroenterology
University of North Carolina at Chapel Hill


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